NHMRC Project Grants; ARC Linkage Project; ARC Discovery Project; ARC LIEF Grants; Cancer Council WA
Please see http://bondxray.org/
English and German
Charlie Bond first became interested in chemistry at school in the United Kingdom and went on to study at the University in Manchester. After completing his PhD on the structure of proteins he pursued this field as a post-doctoral researcher in Sydney and as a research fellow at the School of Life Sciences, University of Dundee, UK. He was recruited to UWA as a structural biologist in 2006. In addition to researching the structure of biomolecular complexes he has also developed and published related computer software programs.
Prospective Research Students, with good prospects of gaining a scholarship, and interested in understanding the role of structure in gene regulation, RNA recognition and enzyme function are always sought in my lab. Please see bondxray.org for more information.
Undergraduate units, honours supervision and PhD supervision in both Chemistry and Biochemistry.
Roles and responsibilities
Protein chemistry - Structural biology - Molecular biology - Biological chemistry - Protein:protein interactions - Protein:RNA interactions - Crystallography - Computational modelling - Biophysics - Synchrotron science
Structure-based methods of studying proteins form the basis of any mechanistic approach to drug design and evaluation, as typified by pharmaceuticals such as Relenza and Gleevec.
|As a structural biologist, Prof. Bond studies the three dimensional structure of biological molecules, such as nucleic acids and proteins, which helps to explain how the molecules function. The applications of Prof. Bond’s studies are very broad and far reaching. Protein structures can be used as a basis to design drugs to treat infectious diseases, and researching how proteins contribute to errors in DNA and RNA expression increases our understanding of how cancers and other disorders are caused, and how they might be treated.|
Research expertise keywords
- Enzyme structure, function and inhibition
- Mechanisms of DNA repair
- Protein crystallography
- Protein–nucleic acid interactions
- Structural biology