Research Output per year
Dr. Laird studies the pathogenesis of movement disorders with a particular focus on identifying and testing potential disease treatments. Her group has been successful at producing and characterising the world’s first zebrafish model of spinocerebellar ataxia type-3 (also known as Machado Joseph Disease, MJD). They are currently testing the effect of various drugs on these zebrafish with the aim of identifying a treatment for the disease.
Dr. Laird's full CV, with all grants and activities, can be accessed here.
- Developing transgenic zebrafish models of neurodegenerative diseases such as spinocerebellar ataxia-3 and motor neuron disease
- Role of proteolytic cleavage in the pathogenesis of spinocerebellar ataxia-3
- Potential of autophagy induction for the treatment of spinocerebellar ataxia-3
- Role of glutamate induced excitotoxicity in the pathogenesis of spinocerebellar ataxia-3
Senior Research ScientistJan 2010 → Feb 2016
Postdoctoral FellowMay 2008 → Oct 2010
Casual Admin/Research AssistantJan 2002 → Jan 2007
The redox activity of protein disulfide isomerase inhibits ALS phenotypes in cellular and zebrafish modelsParakh, S., Shadfar, S., Perri, E. R., Ragagnin, A. M. G., Piattoni, C. V., Fogolín, M. B., Yuan, K. C., Shahheydari, H., Don, E. K., Thomas, C. J., Hong, Y., Comini, M. A., Laird, A. S., Spencer, D. M. & Atkin, J. D., 22 May 2020, In : iScience. 23, 5, p. 1-27 44 p., 101097.
Research output: Contribution to journal › Article › Research › peer-review