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Personal profile

Biography

Alison Rodger moved to Macquarie in 2017 after over 20 years at the University of Warwick. Her research focuses on understanding the structure and function of biomacromolecules and their assemblies. Her particular expertise is with spectroscopic biophysical methods particularly circular dichroism and linear dichroism in the UV, visible and infra red regions of the spectrum for use with nucleic acids, proteins, lipids, and carbohydrates. She designs and applies new techniques to understand how biomolecules interact. She is currently working to understanding molecular aspects of bacterial cell-division and to develop and apply Raman Linear Difference Spectroscopy which she invented and various forms of infra-red spectroscopy. At Macquarie she is establishing an open access biophysical spectroscopy laboratory for collaborators and commercial users.

Alison received her BSc, PhD and DSc from Sydney University, her MA from Oxford, a DSc from Warwick, and her BA from Chester. She was a Beatrice Dale Fellow at Newnham College Cambridge for three years from 1985 while also an Overseas Scholar of the Royal Commission for the Exhibition of 1851. Alison then spent six years in Oxford as Unilever Fellow at St Catherine's College and Violette and Samuel Glasstone Fellow at St Hilda’s. At that time she set up the first Couette flow linear dichroism facilities in the UK and began her programme of analytical science method development for biomacromolecules.

At the University of Warwick Alison was the founding director of the Molecular Organisation and Assembly in Cells Doctoral Training Centre funded by the Engineering and Physical Sciences Research Council and also the head of the Department of Chemistry. She is passionate about supporting early career researchers, especially those working across disciplines and is a member of the Plotina EU network which is funded by Horizon 2020 to facilitate the development of Gender Equality Plans in Research Performing Organisations. Alison enjoyed every minute of her 4 years on the Royal Society of Chemistry Council which finished in July 2017.

 

Research interests

Solution phase biomacromolecule structure and function

  1. Development of spectroscopic techniques, particularly linear and circular dichroisms and Raman methods, for the study of biomacromolecules.
  2. Structure, function and intermolecular interactions of protein systems, including fibrous and membrane proteins.
  3. Structure and function of DNA, DNA/ligand and DNA/protein systems.
  4. Biophysics of bacterial cell division.

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Research Output

An Escherichia coli twin-arginine signal peptide switches between helical and unstructured conformations depending on the hydrophobicity of the environment

San Miguel, M., Marrington, R., Rodger, P. M., Rodger, A. & Robinson, C., Aug 2003, In : European Journal of Biochemistry. 270, 16, p. 3345-3352 8 p.

Research output: Contribution to journalArticleResearchpeer-review

  • Estrogen-derived steroidal metal complexes: Agents for cellular delivery of metal centers to estrogen receptor-positive cells

    Jackson, A., Davis, J., Pither, R. J., Rodger, A. & Hannon, M. J., 30 Jul 2001, In : Inorganic Chemistry. 40, 16, p. 3964-3973 10 p.

    Research output: Contribution to journalArticleResearchpeer-review